1. A multi-dose ophthalmic composition comprising: a first polyol selected from mannitol, sorbitol, or a combination thereof； a second polyol selected from propylene glycol, glycerol, or a combination thereof； an effective amount of borate, which is less than about 0.5% w / v. of the total composition； BAC as an antimicrobial preservative, wherein the concentration of BAC in the composition is more than 0.0007% w / v, but less than 0.0035% w / v； Ivod. 2. The composition according to claim 1, which meets the requirements of the European Pharmacopoeia A, European Pharmacopoeia B, or both. The composition according to claim 1, wherein the concentration of the first polyol is at least 0.01% w / v, but does not exceed 0.5% w / v. 4. The composition of claim 3, wherein the concentration of the first polyol is less than about 0.35% w / v. 5. A composition according to any one of claims 1 to 4, in which the concentration of BAC is less than 0.0025% w / v of the composition. A composition according to any one of claims 1 to 4, wherein the concentration of BAC is less than 0.0015% w / v of the composition. A composition according to any one of claims 1 to 4, wherein the amount of the second polyol is at least about 0.1, but less than about 5% w / v of the composition. A composition according to any one of claims 1 to 4, in which the first polyol is mannitol. A composition according to any one of claims 1 to 4, which is substantially free of any preservatives other than benzalkonium chloride. A composition according to any one of claims 1 to 4, wherein the stability provided by the composition for normalizing the pH of the tear after intraocular instillation is less than 25 μl of 1 M NaOH / ml of the composition. The composition according to any one of claims 1 to 4, in which stability, provide1. Мультидозовая офтальмологическая композиция, включающая:первый полиол, выбираемый из маннита, сорбита или их комбинации；второй полиол, выбираемый из пропиленгликоля, глицерина или их
