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NOVEL WATER-SOLUBLE PRODRUG
专利权人:
发明人:
申请号:
EP05728811.0
公开号:
EP1757609B1
申请日:
2005.04.08
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
An objective of the present invention is to provide water-soluble prodrugs that can be administered parenterally, and which show excellent water solubility and small interspecies or individual differences and are rapidly converted to the active form by chemical conversion. This invention provides water-soluble prodrugs represented by formula (1), or pharmaceutically acceptable salts, or hydrates or solvates thereof,(wherein,R1 represents a hydrogen atom, or C1-C6 alkyl groupW represents a divalent group comprising a tertiary amino group or sulfonyl group andY represents a residue of a compound represented by Y-OH comprising an alcoholic hydroxyl group).
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