Bharathikumar Vellalore Maruthachalam,Aynan Elsayed Mohammad,Jianghai Liu,Humphrey Fonge,Kris Barreto,Clarence Ronald Geyer
申请号:
US16637201
公开号:
US20200207868A1
申请日:
2018.08.09
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure is directed to antibodies and binding fragments thereof that specifically bind HER3. The disclosure is further directed to immunoconjugates comprising the antibodies and binding fragments thereof that specifically bind HER3. The disclosure is also directed to uses of the antibodies, binding fragments thereof and immunoconjugates for detecting HER3-expressing cells and for treating HER3-expressing cancer.