Matthew Bio,Sebastien Caille,Brian Cochran,Yuanqing Fang,Filisaty Vounatsos,Sarah Wortman
申请号:
US15163186
公开号:
US09855259B2
申请日:
2016.05.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.