PROCESSES OF MAKING AND CRYSTALLINE FORMS OF A MDM2 INHIBITOR

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专利权人:

AMGEN INC

发明人:

WORTMAN SARAH,WIEDEMANN SEAN,VOUNATSOS FILISATY

申请号：

AP201508891

公开号：

AP201508891A0

申请日:

2014.06.09

申请国别(地区):

AP

年份:

2015

代理人:

摘要：

The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

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中国工程科技知识中心

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