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Methods and apparatus for quantifying color changes induced by specific concentrations of biological analytes
专利权人:
发明人:
Bernard Burg,Martin Zizi,Aaron Alexander Rowe,Anthony Smart,Walter De Brouwer
申请号:
US15081884
公开号:
US09607380B2
申请日:
2016.03.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods and electronic devices for performing color-based reaction testing of biological materials. The method includes capturing and interpreting digital images of an unexposed and later exposed paddle at various delay times within an automatically calibrated environment. The test paddle includes a unique identification mechanism (UID), a Reference Color Bar (RCB) providing samples of standardized colors for image color calibration, compensation and corrections, and several test-specific sequences of Chemical Test Pads (CTP). The method further includes locating the paddle in the image, extracting the UID and validating the paddle, extracting the RCB and locating the plurality of CTP in each image. The method further reduces image noise in the CTP and calibrates the image automatically according to lighting measurements performed on the RCB. To determine test results, the method further determines several distances between the CTP and its possible trajectory in the color space described by the Manufacturer Interpretation Color Chart.
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