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DERIVATIVES OF UNCIALAMYCIN, METHODS OF SYNTHESIS AND THEIR USE AS ANTITUMOR AGENTS
专利权人:
发明人:
申请号:
EP14758223.3
公开号:
EP3033346A1
申请日:
2014.08.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
In one aspect, the present disclosure provides new analogs of uncialamycin of formulae (I) and (II). The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates comprising the compounds of formulae (I) and (II).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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