PROTÉINES DE FUSION IMMUNOGLOBULINE-INSULINE

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专利权人:

The California Institute for Biomedical Research

发明人:

申请号：

EP16843113.8

公开号：

EP3344278A4

申请日:

2016.09.02

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.

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