C-3 ALKYL AND ALKENYL MODIFIED BETULINIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF HIV

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专利权人:

发明人:

申请号：

EP14710687.6

公开号：

EP2958930A1

申请日:

2014.02.21

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV: a compound of Formula I a compound of Formula II a compound of Formula III and a compound of Formula IV The compounds are useful for the treatment of HIV and AIDS.

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