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C-3 ALKYL AND ALKENYL MODIFIED BETULINIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF HIV
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
SWIDORSKI, JACOB,CHEN, YAN,SIT, SING-YUEN,MEANWELL, NICHOLAS A.,REGUEIRO-REN, ALICIA,CHEN, JIE,LIU, ZHENG,HARTZ, RICHARD, A.,XU, LI
申请号:
SG11201506445P
公开号:
SG11201506445PA
申请日:
2014.02.21
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV: a compound of Formula I a compound of Formula II a compound of Formula III and a compound of Formula IV The compounds are useful for the treatment of HIV and AIDS.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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