Harriet Robinson,Arban Domi,Michael Hellerstein,Farshad Guirakhoo,Nathanael Paul McCurley
申请号:
US16796350
公开号:
US20200289633A1
申请日:
2020.02.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases