FUSED RING PYRROLIDINE DERIVATIVES

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专利权人:

DAINIPPON SUMITOMO PHARMA CO.; LTD.

发明人:

TAKAI, KENTARO,高井健太郎,高井健太郎,SUMIYOSHI, TAKAAKI,住吉孝明,住吉孝明,SUWA, ATSUSHI,诹访笃志,諏訪篤志,TAKAHASHI, YOKO,高桥洋子,高橋洋子,URUNO, YOSHIHARU,宇留野义治,宇留野義治,MURATA, YASUKO,村田康子,村田康子

申请号：

TW100128502

公开号：

TW201211028A

申请日:

2011.08.10

申请国别(地区):

TW

年份:

2012

代理人:

摘要：

This invention provides a fused ring pyrrolidine derivative, which exhibits an effect of acting on muscarinic receptors M1, and M4 with selectivity, meanwhile decreases side effects of mediating through other muscarinic receptors or other receptors.This invention relates to a compound represented by formula (1)or pharmaceutically allowable salt thereof, a pharmaceutical composition comprising the same as active ingredient, and a prophylactic agent and/or treating agent of muscarnic receptors mediated diseases comprising the same.本發明係提供一種縮環吡咯啶衍生物,其顯現選擇性地作用於蕈毒鹼M1及M4受體的效果,並減低透過其他的蕈毒鹼受體或其他的受體的副作用。本發明係關於式(1)所示之化合物或其藥學上容許的鹽、以該等為有效成分之醫藥組成物、及含有該等之蕈毒鹼受體媒介疾病之預防及/或治療劑。(式中各代號如說明書所述。)

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/