Sergei Nedospasov,Andrey Kruglov,Grigory Alexandrovich Efimov
申请号：
US14438288
公开号：
US09688757B2
申请日:
2013.10.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates to isolated bispecific affinity reagents, such as antibodies or antibody fragments that bind TNFα and a marker molecule for macrophages and/or neutrophils. The affinity reagents of the invention enable pathogenic sub-populations of TNFα to be neutralized, while protective sub-populations of TNFα are not affected.
