Alessandro ACCETTA,Fabio RANCATI,Anna Maria CAPELLI,David Edward CLARK,Patrizia TISSELLI,Christine EDWARDS,Gurdip BHALAY,Arnaud Jean Francois Auquste CHEGUILLAUME
申请号：
US16656842
公开号：
US20200079774A1
申请日:
2019.10.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Bicyclic dihydropyrimidine-carboxamide compounds of formula I described herein inhibit Rho Kinase and may be used for the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
