Alessandro Accetta,Fabio Rancati,Anna Maria Capelli,David Edward Clark,Patrizia Tisselli,Christine Edwards,Gurdip Bhalay,Arnaud Jean Francois Auguste Cheguillaume
申请号：
US15883729
公开号：
US20180215758A1
申请日:
2018.01.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Bicyclic dihydropyrimidine-carboxamide compounds of formula I described herein inhibit Rho Kinase and may be used for the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
