ALMENA-PEREA JUAN JOSE,BRINK MONIKA,GEISS GERHARD,KADYROV RENAT,MEYER THORSTEN,Almena-Perea Juan Jose,Brink Monika,Geiss Gerhard,Kadyrov Renat,Meyer Thorsten
申请号：
SI200831309
公开号：
SI2109614T1
申请日:
2008.01.31
申请国别(地区):
SI
年份:
2014
代理人:
摘要：
This invention relates to a process for the hydrogenation of a ketooxime to selectively form an aminoalcohol stereoisomer, and, in particular, to a process for the hydrogenation of 4,5-dihydro-imidazo[4,5,1-jk][1]benzazepin-2,6,7[1H]-trione-6-oxime or a salt thereof to selectively form a stereoisomer of 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one or a salt thereof. This invention also relates to the use of the 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one hydrogenation product or a salt thereof to selectively make a stereoisomer of zilpaterol or a salt thereof, as well as the use of such a zilpaterol stereoisomer or salt in methods of treatment and medicaments for animals.
