Vincent Guerlavais;Qian Zhang;Bilal Sufi;David B. Passmore;Liang Chen;Sanjeev Gangwar
发明人:
Bilal Sufi,Vincent Guerlavais,Liang Chen,Sanjeev Gangwar,Qian Zhang,David B. Passmore
申请号:
US12521391
公开号:
US08461117B2
申请日:
2007.12.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.