SUFI, BILAL,GUERLAVAIS, VINCENT,CHEN, LIANG,GANGWAR, SANJEEV,ZHANG, QIAN,PASSMORE, DAVID, B
申请号:
NZ57832407
公开号:
NZ578324A
申请日:
2007.12.28
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are compounds of formula (I) wherein the substituents are disclosed within the specification. The disclosed compounds involve linkers and cleavable substrates that attach to a drug and a ligand and are cleaved in vivo. The linkers and cleavable substrates are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as other diagnostic and therapeutic moieties.