Sharon E. Boyd,Liang Chen,Sanjeev Gangwar,Vincent Guerlavais,Kilian Horgan,Zhi-Hong Li,Bilal Sufi
申请号：
US12610952
公开号：
US08399403B2
申请日:
2009.11.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine, or disulfide linker. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
