DERIVES DE PYRAZOLE, COMPOSITION DE MEDICAMENT CONTENANT CES DERIVES, UTILISATION MEDICALE DE CES DERIVES ET INTERMEDIAIRE POUR LA PRODUCTION DE CES DERIVES
The present invention provides pyrazole derivativesrepresented by the general formula:(see formula I)wherein R1 represents H, an optionally substituted C1-6 alkylgroup etc.; one of Q and T represents a group represented bythe general formula:(see formula II)or a group represented by the general formula:(see formula III)while the other represents an optionally substituted C1-6 alkylgroup etc.; R2 represents H, a halogen atom, OH, an optionallysubstituted C1-6 alkyl group etc.; X represents a single bond,O or S; Y represents an optionally substituted C1-6 alkylenegroup etc.; Z represents -R B, COR C etc. in which R B representsan optionally substituted C1-6 alkyl group etc.; and R C representsan optionally substituted C1-6 alkyl group etc.,; R4 representsH, an optionally substituted C1-6 alkyl group etc.; and R3, R5and R6 represent H, a halogen atom etc., pharmaceuticallyacceptable salts thereof or prodrugs thereof, which exhibit anexcellent inhibitory activity in human SGLT1 and are useful asagents for the prevention or treatment of a disease associatedwith hyperglycemia such as diabetes, impaired glucose tolerance,impaired fasting glycemia, diabetic complications or obesity,and a disease associated with the increase of blood galactoselevel such as galactosemia, and pharmaceutical compositionscomprising the same, pharmaceutical uses thereof, andintermediates for production thereof.