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ETHYNYL COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC USE FOR THE TREATMENT OF MALARIA
专利权人:
SANOFI
发明人:
Cécile PASCAL,Alain PELLET,Gilles COURTEMANCHE,SIMON CAMPBELL
申请号:
US16628720
公开号:
US20200281909A1
申请日:
2018.07.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein R1 means a fluorine atom or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms; R2 means a chlorine atom, a linear alkyl radical containing 1, 2 or 3 carbon atoms or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms, and R means a hydrogen atom or a radical of formula (Ia). The present disclosure also relates to processes for their preparation as well their therapeutic uses, in particular such as for use in the treatment of malaria.
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