A connection device (1) with improved safety and protection, to connect two ends of respective ducts (5, 6) to another flexible duct (7) in particular in the field of the peritoneal dialysis comprises: a closed container (2) containing two nozzle-like terminal ends (9) of a Y-shaped branch (8) of a flexible duct (7) a removable connection member (3) apt to be engaged/disengaged on said closed container (2), containing the ending portions of the respective ducts (5, 6) shaped to couple/uncouple with said nozzle-like terminal ends (9), a distal end of the container (2) and the connecting member (3) being shaped to couple according to a guiding scheme with prismatic joint a closure with mobile walls (29) on said closed container (2) actuated in opening and closing by the contact of a projecting septum (33) of said connection member (3) upon the connection/disconnection between said closed container (2) and said connection member (3) and a closure with removable tear film (37) arranged at the ending portions (10) of said ducts (5, 6) to close the respective sections opened inside said connection member (3), apt to be removed from the interference between the edge of said closed container (2) and a thickened edge thereof (38) upon the connection between said closed container (2) and said connection member (3), the connection of said closed container (2) and said connection member (3) determining the engagement and the disengagement of said nozzle-like terminal ends (9) with said ending portions of respective ducts (5, 6).Un dispositivo de conexión (1) con seguridad y protección mejoradas, para conectar dos extremos de ductos (5, 6) respectivos con otro ducto flexible (7) en particular en el campo de la diálisis peritoneal comprende: un contenedor cerrado (2) que contiene dos extremos terminales tipo boquilla (9) de una ramificación en forma de Y (8) de un ducto flexible (7) un miembro de conexión removible (3) apto para ser acoplado/desacoplado en dicho contenedor cerrad