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MOLÉCULES DE LIAISON POUR BCMA ET CD3
专利权人:
Amgen Research (Munich) GmbH;Amgen, Inc
发明人:
申请号:
EP19196304.0
公开号:
EP3611193A1
申请日:
2012.11.15
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.
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