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MOLECULES DE LIAISON POUR BCMA ET CD3
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;AMGEN RESEARCH (MUNICH) GMBH
发明人:
KUFER, PETER,RAUM, TOBIAS,HOFFMANN, PATRICK,KISCHEL, ROMAN,LUTTERBUESE, RALF,RAU, DORIS,ADAM, PAUL,BORGES, ERIC,HEBEIS, BARBARA,HIPP, SUSANNE
申请号:
CA2849196
公开号:
CA2849196A1
申请日:
2012.11.15
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain,wherein the first binding domain is capable of binding to epitope cluster3 of BCMA,and the second binding domain is capable of binding to the Tcell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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