BOEHRINGER INGELHEIM INTERNATIONAL GMBH;AMGEN RESEARCH (MUNICH) GMBH;AMGEN INC.
发明人:
申请号:
IL23260314
公开号:
IL232603A
申请日:
2014.05.13
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope clusters of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.