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MOLECULES DE LIAISON POUR BCMA ET CD3
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;AMGEN RESEARCH (MUNICH) GMBH
发明人:
KUFER, PETER,RAUM, TOBIAS,HOFFMANN, PATRICK,KISCHEL, ROMAN,LUTTERBUESE, RALF,RAU, DORIS,ADAM, PAUL,BORGES, ERIC,HEBEIS, BARBARA,HIPP, SUSANNE
申请号:
CA2850591
公开号:
CA2850591A1
申请日:
2012.11.15
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope clusters of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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