Antifungal agent for external use safely without side effects in a short period of time yet inexpensive to resolve individual differences in the treatment as well as a possible treatment without restriction even for patients of lactating and pregnant women and patients with underlying diseases, such as liver disease edge for adhesion as well are provided in the opening of the dome-shaped applicator is intended for the purpose of allowing percutaneous absorption effectively deep into the nail from the nail surface, the membrane of the opening periphery After sealing bonded to the surface of the nail dome applicator comprising a flexible member which is formed thicker than the membrane of the other part thick and antifungal liquid domed applicator press-fitting device or the like from the outside is infiltrated deep into the nail efficiently antifungal external preparation by using a positive pressure to press-fit the external preparation.肝臓疾患など基礎疾患がある患者や妊婦および授乳中の患者に対しても制限なく治療が可能であるとともに治療における個体差を解決し短期間で副作用がなくしかも安価で安全に抗真菌外用剤を爪表面から爪の深部にまで効率的に経皮吸収させることを目的とするものでありドーム型アプリケータの開放部に接着のための縁部が設けられているとともに、開放周辺部の膜の厚さが他の部分の膜よりも厚く成形された可撓性部材からなるドーム型アプリケータを爪の表面に密封接着した後、外部から圧入器等でドーム型アプリケータ内に液体の抗真菌外用剤を圧入し陽圧を利用して抗真菌外用剤を効率的に爪の深部に浸透させる。
