A removal agent for removing nail polish coating is disclosed, which comprises Hydroxyethyl Cellulose (HEC) and solvent, wherein the solvent can be acetone, Methyl Ethyl Ketone (MEK), ethyl acetate or a combination thereof. When the removal agent is applied and coated onto the coating layer of the nail surface, a surface thin film will be formed naturally once the removing agent has contacted air for preventing the solvent from vaporization, thereby enabling the solvent not to be easily vaporized and skipping complicated removing steps including aluminum foils covering. Moreover, the removing agent is able to remove effectively the coating layer formed by nail gel, and also remove easily the coating layer formed by nail polish.一種用於去除指甲表面塗層的卸除劑,包含乙基纖維素及溶劑,其中,該溶劑是選自於丙酮、丁酮、乙基醋酸酯或前述的一組合。當本發明卸除劑塗敷並覆蓋於指甲表面塗層上,經與空氣接觸後將自然形成一表面薄膜而不易讓溶劑揮發,藉此可讓溶劑不易揮發並可省略覆蓋錫箔紙等繁瑣去除步驟,還能有效去除光療指甲油所形成的塗層,更可輕易去除一般指甲油所形成的塗層。