GRACZYK PIOTR PAWEL;DIMOPOULOS PASCHALIS;KHAN AFZAL;BHATIA GURPREET SINGH;FARTHING CHRISTOPHER NEIL;EISAI R&D MANAGEMENT CO., LTD.
发明人:
GRACZYK PIOTR PAWEL,DIMOPOULOS PASCHALIS,KHAN AFZAL,BHATIA GURPREET SINGH,FARTHING CHRISTOPHER NEIL
申请号:
US20090536342
公开号:
US8178552(B2)
申请日:
2009.08.05
申请国别(地区):
美国
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula (I); or a pharmaceutically acceptable salt thereof, the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in the inhibition of c-Jun N-terminal kinase (JNK) activity and the use in medicine and particularly in the treatment of neurodegenerative disorders, inflammatory diseases and/or and autoimmune diseases. The invention also provides processes for the manufacture of said compounds of formula (I) or a pharmaceutically acceptable salt thereof and compositions containing them.