SHIMOKAWADOKO YASUTAKA,CRAEN MARC VAN DE,NOOREN IRENE,TURCONI SANDRA,ROOBROUCK ANNELIES,MADDELEIN WENDY
申请号:
JP20050183032
公开号:
JP2007000061(A)
申请日:
2005.06.23
申请国别(地区):
日本
年份:
2007
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a search method of agricultural chemicals defining a target, i.e., a method for screening compounds with activity to the specific target for the purpose of chemically adjusting target parts which can control insects and noxious organism, or the like. SOLUTION: Medicine gives change to physical state of noxious organism and has an ability to change the activity of c-Jun NH2-terminal kinase (hereinafter, the enzyme) derived from an insect. The screening method of noxious organism-preventing ability of a material to be examined comprises, for instance, (1) a first process of measuring the activity of the enzyme in a contact system between the enzyme selected from the group (A) including protein or the like composed of a disclosed amino acid sequence, and the material to be examined, and (2) a second process of evaluating the noxious organism-preventing ability of the material based on a difference obtained by comparing the activity measured in the first process with activity in contrast. COPYRIGHT: (C)2007,JPO&INPIT