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COMPOSITIONS FOR HERPESVIRUS TRANSCRIPTIONAL FEEDBACK CIRCUIT DISRUPTION AND USES THEREOF
专利权人:
The J. David Gladstone Institutes; a testamentary trust established under the Will of J. David Glads
发明人:
Leor S. Weinberger,Sonali Chaturvedi
申请号:
US17251395
公开号:
US20210395746A1
申请日:
2019.06.12
申请国别(地区):
US
年份:
2021
代理人:
摘要:
The present disclosure provides compositions and methods for inhibiting herpesvirus replication in a cell infected with herpesvirus. The composition includes a double stranded DNA molecule including a sequence of a cis regulatory sequence (crs) of a herpesvirus, wherein the crs is flanked on the 5′ end by a first sequence of at least 2 base pairs and on the 3′ end by a second sequence of at least 2 base pairs.
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