GLUNZ, Peter W.,LADZIATA, Vladimir,DE LUCCA, Indawati,TORA, George O.,MAISHAL, Tarun Kumar,TANGIRALA, Raghuram,THIYAGARAJAN, Kamalraj
申请号:
AU2018300094
公开号:
AU2018300094A1
申请日:
2018.07.11
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.