PUHL, MICHAEL,DITRICH, KLAUS,KELLER, ANDREAS,DIMITROVA, PEPA,WEINGARTEN, MELANIE,SIEGEL, WOLFGANG
申请号：
CA2960056
公开号：
CA2960056A1
申请日:
2015.09.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to a method for preparing 2'-O-fucosyllactose, the 2'-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C1-C6-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base. In the formulae (I) and (II), the variables are each defined as follows: RSi are the same or different and are a residue of the formula SiRaRbRc； R1 is a C(=O)-R11 residue or an SiR12R13R14 residue, R2 are the same or different and are C1-C8-alkyl or together form a linear C3-C6- alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents； R3 are the same or different and are C1-C8-alkyl or together form a linear C1-C4- alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents.
