The detector which compares the physiology signal which is detected the brain (3B) with the detector which detects inviting occurrence or the spontaneous characteristic physiology signal which occurs (10), making use of the standard in order to decide the optimum specification of variable signal parameter (10) the control control equipment which is connected (12), the electric stimulus signal (EES) the 1st signal generator which is impressed in the person (2) (8), and/or the feeling stimulus signal (SSS) the person (2) the sensitive organ (3A) one which is impressed 2nd signal generator (9), to have at least, the stimulus signal(ESS and SSS) signal parameter is adjusted the optimum specification to which this signal parameter is decided, the person (2) the brain (3B) the device which is stimulated.脳(3B)で発生される誘発性または自発性の生理学的信号を検出する検出器(10)、可変信号パラメータの最適設定値を決定するための基準を用いて検出された生理学的信号を比較する検出器(10)に接続されている制御装置(12)、電気刺激信号(EES)をヒト(2)に印加する第1の信号発生器(8)、および/または感覚刺激信号(SSS)をヒト(2)の感覚器官(3A)に印加する少なくとも1つの第2の信号発生器(9)、を備え、刺激信号(ESS、SSS)の信号パラメータはこの信号パラメータの決定された最適設定値に調整される、ヒト(2)の脳(3B)を刺激する装置。