PROBLEM TO BE SOLVED: To perform a necessary amount of nerve stimulation while reducing bad influence on a heart.SOLUTION: The nerve stimulation device 1 includes: a storage part 7 storing a maximum value of a nerve stimulation signal two or more stimulation electrodes 2a, 2b disposed in a nerve N a stimulation signal output part 4 outputting the nerve stimulation signal corresponding to the maximal value stored in the storage part 7 to between the stimulation electrodes 2a, 2b two or more detection electrodes 3a-3d disposed in the heart H a potential difference measurement part 5 measuring a potential difference between two of the stimulation electrodes 2a, 2b and the detection electrodes 3a-3d and a maximum value adjustment part 6 updating the maximum value of the nerve stimulation signal stored in the storage part 7 based on the potential difference measured by the potential difference measurement part 5.COPYRIGHT: (C)2012,JPO&INPIT【課題】心臓への悪影響を軽減しつつ、必要量の神経刺激を行う。【解決手段】神経刺激信号の最大値を記憶する記憶部7と、神経Nに配置された2以上の刺激電極2a,2bと、該刺激電極2a,2b間に、記憶部7に記憶されている最大値に応じた神経刺激信号を出力する刺激信号出力部4と、心臓Hに配置された2以上の検出電極3a~3dと、刺激電極2a,2bおよび検出電極3a~3dのうちのいずれか2つの間の電位差を測定する電位差測定部5と、該電位差測定部5により測定された電位差に基づいて、記憶部7に記憶されている神経刺激信号の最大値を更新する最大値調節部6とを備える神経刺激装置1を提供する。【選択図】図1