PROCESS FOR THE DETECTION AND/OR DETERMINATION OF COMPONENTS OF THE REACTION BETWEEN A SPECIFIC BINDING PROTEIN AND THE CORRESPONDING BINDABLE SUBSTANCE IN AN AQUEOUS TEST SAMPLE;FREEZE-DRIED REAGENT AND TEST KIT TO BE USED IN THE PROCESS
- 专利权人:
- AKZO N.V.
- 发明人:
- 申请号:
- IE19790001315
- 公开号:
- IE48467(B1)
- 申请日:
- 1979.08.08
- 申请国别(地区):
- 爱尔兰
- 年份:
- 1985
- 代理人:
- 摘要:
A method, test kit and labeled component for the detection and/or determination of one or more components of the reaction between a specific binding protein and the corresponding bindable substance, in which one or more labelled components are used, that are obtained by coupling particles of a dispersion of a metal, metal compound or polymer nuclei, coated with a metal or metal compound, having a particle size of at least 5 nm, directly or indirectly to the desired component of said reaction. During the reaction or after an adequate reaction time, the physical properties and/or the amount of the metal and/or the formed metal containing agglomerate, is/are determined in the test sample, or optionally after a separation of the bound and free metal-labelled components in one of the derived fractions by methods known as known by those skilled in the immunoassay field.
- 来源网站:
- 中国工程科技知识中心