PROBLEM TO BE SOLVED: To provide an erythrocyte depletion inhibitor, a food additive, and a food or drink which are excellent in the inhibitory effect on erythrocyte depletion and which can be produced by a simple method. The red blood cell depletion inhibitor of the present invention contains sudatin. The food additive of the present invention may include the erythrocyte depletion inhibitor. The food or drink of the present invention may contain the food additive. The red blood cell depletion inhibitor according to the present invention has an excellent effect of suppressing red blood cell depletion, and can be produced by a simple method. The food additive of the present invention is useful as an additive for various foods and drinks. [Selection diagram] None【課題】赤血球減少の抑制作用に優れ、また、簡便な方法で製造することができる赤血球減少抑制剤、食品添加物及び飲食品を提供する。【解決手段】本発明の赤血球減少抑制剤は、スダチチンを含む。本発明の食品添加物は、前記赤血球減少抑制剤を含むことができる。本発明の飲食品は、前記食品添加物を含むことができる。本発明に係る赤血球減少抑制剤は、赤血球減少の抑制作用に優れ、また、簡便な方法で製造することができる。本発明の食品添加物は、各種飲食品の添加物として有用である。【選択図】なし