IL-37 VARIANTS

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专利权人:

发明人:

申请号：

EP16810615.1

公开号：

EP3307767A1

申请日:

2016.06.15

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This invention relates to polypeptides, including variants of interleukin-37 (IL-37), and related therapeutics and compositions. The invention also relates to the use of the polypeptides and compositions in methods of treating inflammatory diseases or conditions. The present invention provides a monomeric anti-inflammatory polypeptide comprising an amino acid sequence of an IL-37 monomer, the amino acid sequence having a mutation or modification for preventing the anti-inflammatory peptide from forming a homodimer.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/