The present invention relates to the field of aquaculture of commercially important crustaceans such as penaeid shrimp. The present invention discloses a process to effectively infect crustaceans via inoculating pathogens directly into the external pore of the antennal gland of said crustaceans. This new portal of entry for pathogens can be used to investigate and/or prevent infection of crustaceans with pathogens such as white spot syndrome virus.