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A PROCESS FOR THE PURIFICATION OF ESLICARBAZEPINE ACETATE
专利权人:
发明人:
申请号:
EP10758151.4
公开号:
EP2414335A2
申请日:
2010.03.30
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A process for purifying eslicarbazepine acetate is provided The crystalline particles of eslicarbazepine acetate having a median particle size between 5 μm and 20 μm and a specific surface area of from 0.1 m2/g to 10 m2/g as measured by B.E.T. method are obtained Eslicarbazepine acetate having purity greater than 99.0% as measured by high performance liquid chromatography and a pharmaceutical composition containing the same are also provided.La présente invention concerne la purification et la taille particulaire de lacétate deslicarbazépine. Linvention concerne également les caractéristiques physiques de lacétate deslicarbazépine à létat solide, et des compositions pharmaceutiques le contenant.
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