PROCÉDÉS D'UTILISATION DE COMPOSITIONS D'ÉPITOPE DE LYMPHOCYTES B À FAIBLE VOLUME DE DOSE POUR INDUIRE UNE RÉPONSE IMMUNITAIRE À ANTICORPS CHEZ DES SUJETS HUMAINS
MANSOUR, Marc,ORS, Frederic,STANFORD, Marianne,SAMMATUR, Leeladhar,RAJAGOPALAN, Rajkannan,MACDONALD, Lisa Diana
申请号：
EP16917017
公开号：
EP3518963A4
申请日:
2016.09.27
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present disclosure provides methods, uses and compositions and kits for use in inducing an antibody immune response in a human subject. The methods and uses involve administering parenterally a low dose volume of a composition comprising an antigen comprising a B-cell epitope, an amphipathic compound, and a hydrophobic carrier, wherein the low dose volume of the composition is less than 100 μl and induces an antibody immune response to the B-cell epitope in the human subject.
