Iso quinoline -6- sulphur vinegar the amine derivatives of the useful Xin Ying of the bright Ti Gong mono- Seed Zuo As Medical Drug of this Hair. The molten Elixirs of represented Iso quinoline -6- sulphur vinegar amine derivative, Qi Which or The of this Hair Ming Department general formulas (1) etc. closes object, and (in formula, R1 and R2 Fen Do Independence are vertical to indicate Hydrogen atoms etc.R3 and R4 Fen Do Independence are vertical to indicate Hydrogen atoms, alkyl etc.R5 indicates Hydrogen atoms, can have substituent group alkyl, the alkynyl that can have substituent group, can have substituent group Ring alkyl, the alkane anilide that can have substituent group etc. at the alkenyl that can have substituent groupA indicates that the straight Chain or branch Chain of 2 ~ 6 Ge of carbon Number stretches alkyl).本發明提供一種作為醫藥有用之新穎之異喹啉-6-磺醯胺衍生物。本發明係通式(1)所表示之異喹啉-6-磺醯胺衍生物、其鹽或該等之溶劑合物(式中,R1及R2分別獨立表示氫原子等;R3及R4分別獨立表示氫原子、烷基等;R5表示氫原子、可具有取代基之烷基、可具有取代基之烯基、可具有取代基之炔基、可具有取代基之環烷基、可具有取代基之烷醯基等;A表示碳數2~6個之直鏈或支鏈伸烷基)。