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Injectable bone regeneration gel containing bone formation enhancing peptide
专利权人:
Chong-Pyoung Chung;Yoon-Jeong Park;Jue-Yeon Lee
发明人:
Chong-Pyoung Chung,Yoon-Jeong Park,Jue-Yeon Lee
申请号:
US12663399
公开号:
US08546529B2
申请日:
2008.06.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to an injectable bone regeneration material containing a bone formation enhancing peptide, and more particularly, to an injectable bone regeneration material, in which a bone formation enhancing peptide essentially containing one and more amino acid sequences among SEQ ID NO: 1 to SEQ ID NO: 28 is bonded or mixed to a gel-forming base material selected from the group consisting of chitosan, alginic acid, silk fibroin, propylene glycol, propylene glycol alginic acid, poloxamer, chondroitin sulphate, and the combination thereof. The injectable bone regeneration material according to the present invention can increase differentiation of bone marrow stromal cells and osteoblasts into bone tissue, thus maximizing tissue regeneration by a peptide capable of promoting differentiation of bone tissue and periodontal tissue regeneration. The injectable bone regeneration material is in the form of a gel, and thus can be applied to a surface of various medical devices such as implant etc., and can be mixed with bone graft particles to apply, so that it can increase a treatment effect of existing medical devices to maximize a tissue regeneration effect.
来源网站:
中国工程科技知识中心
来源网址:
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