Daniel Scott Gierer,James Eric Morgado,Brendan John Murphy,Daryl Michael Simmons
申请号：
US14348415
公开号：
US20140248347A1
申请日:
2012.09.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to pharmaceutical compositions containing axitinib, which is known as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide or 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole, or crystalline forms thereof, that protect axitinib from degradation, including photodegradation, as well as the therapeutic use of such compositions. The present invention also relates to novel photodegradants of axitinib.
