Gierer, Daniel Scott,Morgado, James Eric,Murphy, Brendan John,Simmons, Daryl Michael
申请号:
AU2012313885
公开号:
AU2012313885A1
申请日:
2012.09.26
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to pharmaceutical compositions containing axitinib, which is known as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]- benzamide or 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2- yl)ethenyl]indazole, or crystalline forms thereof, that protect axitinib from degradation, including photodegradation, as well as the therapeutic use of such compositions. The present invention also relates to novel photodegradants of axitinib.