GIERER DANIEL SCOTT,MORGADO JAMES ERIC,MURPHY BRENDAN JOHN,SIMMONS DARYL MICHAEL
申请号:
IN1558/DELNP/2014
公开号:
IN2014DN01558A
申请日:
2014.02.28
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to pharmaceutical compositions containing axitinib, which is known as N-methyl-2-[3- ((E)-2-pyridin-2-yl-vinyl)- lH-indazol-6-ylsulfanyl]- benzamide or 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2- yl)ethenyl]indazole, or crystalline forms thereof, that protect axitinib from degradation, including photodegradation, as well as the therapeutic use of such compositions. The present invention also relates to novel photodegradants of axitinib.