A syringe assembly (10) includes a syringe body (12) including a distal end (13). The syringe body (12) defines a fluid chamber (18) therein. The fluid chamber (18) includes a lower end (17). A septum (19) is disposed at the distal end (13) of the syringe body (12) and is configured to sealingly close the lower end (17) of the fluid chamber (18). The syringe body (12) and the septum (19) are formed as a single, molded piece.