JACOBS, STEVEN A.,O'NEIL, KARYN T.,BAUMANN, MICHAEL,SENNHAUSER, GABY
申请号：
CA2834624
公开号：
CA2834624A1
申请日:
2012.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1 ) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.
