THE JOHNS HOPKINS UNIVERSITY;KENNEDY KRIEGER INSTITUTE, INC.
发明人:
Shilpa D. Kadam
申请号：
US15504141
公开号：
US20170281579A1
申请日:
2015.08.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to the field of seizures. More specifically, the present invention provides compositions and methods for treating refractory seizures in neonates. In one embodiment, the method comprises the steps of (a) administering to the patient an amount of a KCC2 agonist and/or trkB antagonist effective to restore KCC2 expression to normal physiological levels； and (b) administering to the patient an effective amount of an anti-seizure medication.
