PROBLEM TO BE SOLVED: To provide technical means (desirably simple one) for producing a tablet in which the chemical stability of the salt of esomeprazole is improved.SOLUTION: The present invention provides an uncoated tablet having suppressed absorbency in which the metal salt of esomeprazole, and an additive with low absorbency are contained in an amount of 80.0% by weight or more with respect to the total weight of an uncoated tablet, and in which preferably, the additive comprises one or two excipients, one or two disintegrants, one or two binders, and one or two lubricants. The additive with low absorbency includes lactose hydrate, anhydrous lactose, D-mannitol, xylitol, D-sorbitol, maltitol, maltose, sucrose, and powder reduced maltose syrup.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】エソメプラゾールの塩の化学的な安定性等が改善された錠剤を製造するための技術的手段（望ましくは簡便なもの）を提供すること。【解決手段】 エソメプラゾールの金属塩、並びに吸湿性が低い添加剤が素錠の全重量に対して８０．０重量％以上含有され、好ましくは前記の添加剤は１～２種類の賦形剤、１～２種類の崩壊剤、１～２種類の結合剤及び１～２種類の滑沢剤からなる、吸湿量が抑制された素錠を提供する。吸湿性が低い添加剤は、乳糖水和物、無水乳糖、Ｄ－マンニトール、キシリトール、Ｄ－ソルビトール、マルチトール、マルトース、白糖、粉末還元麦芽糖水アメ等が挙げられる。【選択図】なし
